Title of Research
Start Date
17-8-2018 10:00 AM
End Date
17-8-2018 11:30 AM
Abstract
Abstract
Background: Extracorporeal Membrane Oxygenation (ECMO) is an increasingly utilized form of cardiopulmonary life-support therapy to treat patients with severe acute respiratory failure or cardiac failure.
Objectives: The purpose of this review is to describe the overall effectiveness of the current use of ECMO intervention within inpatient hospital settings for pediatric patients, and to explore potential barriers in intervention effectiveness
Method: An integrative literature review was conducted using the following databases: CINHAL, PubMed, and DePaul Libraries Worldwide from January 1, 2008 until August 1, 2018. Search terms included extracorporeal membrane oxygenation, ECMO, extracorporeal life support, ECLS, pediatric, adolescent, infant, neonate, barrier, limitation, finance, adverse effect. This process yielded 22 articles which were examined in this integrative literature review.
Results: Efficacy of ECMO therapy is dependent on the initial indication of use. ECMO for pulmonary resuscitation had a significantly higher survival to discharge rate compared to cardiac resuscitation (76% v. 42%), respectively. Four common adverse physiological effects of patients placed on ECMO therapy were identified: inadequate flow and oxygen delivery, hemolysis, infection, and neurological complications. In addition, institutional policies of volume of utilization and cost were examined for their implication on therapy usage.
Conclusion: Further studies are needed with respect to long-term cohort studies to assess neurological complications, as well as implementation of institutional standardization of protocol (initiation & weaning) in order to improve morbidity and mortality of ECMO therapy.
Included in
Extra Corporeal Membrane Oxygenation (ECMO): A Review of Clinical Indications and Barriers to Efficacy within Acute Care Inpatient Pediatric Populations
Abstract
Background: Extracorporeal Membrane Oxygenation (ECMO) is an increasingly utilized form of cardiopulmonary life-support therapy to treat patients with severe acute respiratory failure or cardiac failure.
Objectives: The purpose of this review is to describe the overall effectiveness of the current use of ECMO intervention within inpatient hospital settings for pediatric patients, and to explore potential barriers in intervention effectiveness
Method: An integrative literature review was conducted using the following databases: CINHAL, PubMed, and DePaul Libraries Worldwide from January 1, 2008 until August 1, 2018. Search terms included extracorporeal membrane oxygenation, ECMO, extracorporeal life support, ECLS, pediatric, adolescent, infant, neonate, barrier, limitation, finance, adverse effect. This process yielded 22 articles which were examined in this integrative literature review.
Results: Efficacy of ECMO therapy is dependent on the initial indication of use. ECMO for pulmonary resuscitation had a significantly higher survival to discharge rate compared to cardiac resuscitation (76% v. 42%), respectively. Four common adverse physiological effects of patients placed on ECMO therapy were identified: inadequate flow and oxygen delivery, hemolysis, infection, and neurological complications. In addition, institutional policies of volume of utilization and cost were examined for their implication on therapy usage.
Conclusion: Further studies are needed with respect to long-term cohort studies to assess neurological complications, as well as implementation of institutional standardization of protocol (initiation & weaning) in order to improve morbidity and mortality of ECMO therapy.