Title of Research
Wilms Tumor Survivorship: Does Childhood Cancer Treatment Predict Late-Term Adverse Effects?
Start Date
23-8-2019 9:00 AM
Abstract
Abstract
Background: Wilms tumor is the leading cancer to affect the kidneys in children most commonly between the age of 3 and 5 years old. Treatment of Wilms tumor typically consists of chemotherapy, radiation, or a combination of the two – which are often successful in eradicating the cancer. However, current treatment options often leave patients with a high risk of late-term adverse effects such as cardiac diseases or secondary cancers later in life. Wilms’ tumor patients currently have a 90% survival rate from their disease, however face a future of indeterminate health problems due to their treatment regimen.
Objectives: The purpose of this literature review is to further examine late-term side effects experienced by childhood Wilm’s tumor survivors in hopes that practitioners will take strides to seek treatment that will lower the likelihood of future diseases. Methods: This literature review was conducted using the DePaul University Library, with sources including CINAHL, CDC Data and Statistics and CA: A Cancer Journal for Clinicians.
Findings: Studies determined that late—term adverse effects are common in cancer survivors due to the rigorous chemotherapy and radiation treatments being administered. The review suggested that in order to control late-term side effects, lifetime monitoring and follow up care needs to be provided in order to provide preventative care and early detection of diseases that may arise due to previous treatment. Conclusion: This review further examined the importance of determining the future effects of rigorous cancer treatment options such as chemotherapy and radiation for pediatric patients with Wilms’ tumor. While the high survival rate for these patients is reassuring for their prognosis, life-long yearly monitoring and early disease screenings need to be done in order to foresee any late-term side effects that are seemingly expected after a child endures cancer treatment. While there is sufficient research about Wilms’ tumor and how to treat these patients effectively, more research needs to be done in order to determine what late-term side effects can be expected. Similarly, more research may help clinicians determine how to treat these patients with hopes of avoiding these effects.
Wilms Tumor Survivorship: Does Childhood Cancer Treatment Predict Late-Term Adverse Effects?
Abstract
Background: Wilms tumor is the leading cancer to affect the kidneys in children most commonly between the age of 3 and 5 years old. Treatment of Wilms tumor typically consists of chemotherapy, radiation, or a combination of the two – which are often successful in eradicating the cancer. However, current treatment options often leave patients with a high risk of late-term adverse effects such as cardiac diseases or secondary cancers later in life. Wilms’ tumor patients currently have a 90% survival rate from their disease, however face a future of indeterminate health problems due to their treatment regimen.
Objectives: The purpose of this literature review is to further examine late-term side effects experienced by childhood Wilm’s tumor survivors in hopes that practitioners will take strides to seek treatment that will lower the likelihood of future diseases. Methods: This literature review was conducted using the DePaul University Library, with sources including CINAHL, CDC Data and Statistics and CA: A Cancer Journal for Clinicians.
Findings: Studies determined that late—term adverse effects are common in cancer survivors due to the rigorous chemotherapy and radiation treatments being administered. The review suggested that in order to control late-term side effects, lifetime monitoring and follow up care needs to be provided in order to provide preventative care and early detection of diseases that may arise due to previous treatment. Conclusion: This review further examined the importance of determining the future effects of rigorous cancer treatment options such as chemotherapy and radiation for pediatric patients with Wilms’ tumor. While the high survival rate for these patients is reassuring for their prognosis, life-long yearly monitoring and early disease screenings need to be done in order to foresee any late-term side effects that are seemingly expected after a child endures cancer treatment. While there is sufficient research about Wilms’ tumor and how to treat these patients effectively, more research needs to be done in order to determine what late-term side effects can be expected. Similarly, more research may help clinicians determine how to treat these patients with hopes of avoiding these effects.