Presenter Information

Leann PodskalanFollow

Start Date

22-3-2019 10:00 AM

End Date

22-3-2019 11:30 AM

Description

Abstract

Background: Acute ischemic stroke is becoming a prevalent problem in our country debilitating many individuals annually. With administration of t-PA in these individuals within the appropriate time frame of symptom onset, cognitive and physical disability can be minimized. Research suggests that t-PA administration within 3 to 4.5 hours of symptom onset can also decrease the occurrence of future acute ischemic stroke.

Objectives: The objective of this integrative literature review is to investigate the potential for recurrence of future ischemic strokes in the case of patients experiencing an acute ischemic stroke that receive t-PA treatment within the allotted administration window.

Methods: This integrative literature review will utilize the matrix method for data synthesis and further reduce, display, and compare the data.

Conclusion: The literature review determined that inadequate numbers of studies have been investigated whether t-PA administration following an acute ischemic stroke, will aid in prevention of future acute ischemic strokes.

Importance to Nursing Practice: This integrative literature review proposal offers a starting point for future direction in acute ischemic stroke and t-PA research. Studies utilized for support can be further investigated to see how t-PA could be a predictor for decreasing prevalence of future strokes after an initial acute ischemic stroke.

Keywords: acute ischemic stroke, t-PA, tissue plasminogen activator, stroke recurrence

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Mar 22nd, 10:00 AM Mar 22nd, 11:30 AM

Tissue Plasminogen Activator and Stroke Recurrence: An Integrative Literature Review

Abstract

Background: Acute ischemic stroke is becoming a prevalent problem in our country debilitating many individuals annually. With administration of t-PA in these individuals within the appropriate time frame of symptom onset, cognitive and physical disability can be minimized. Research suggests that t-PA administration within 3 to 4.5 hours of symptom onset can also decrease the occurrence of future acute ischemic stroke.

Objectives: The objective of this integrative literature review is to investigate the potential for recurrence of future ischemic strokes in the case of patients experiencing an acute ischemic stroke that receive t-PA treatment within the allotted administration window.

Methods: This integrative literature review will utilize the matrix method for data synthesis and further reduce, display, and compare the data.

Conclusion: The literature review determined that inadequate numbers of studies have been investigated whether t-PA administration following an acute ischemic stroke, will aid in prevention of future acute ischemic strokes.

Importance to Nursing Practice: This integrative literature review proposal offers a starting point for future direction in acute ischemic stroke and t-PA research. Studies utilized for support can be further investigated to see how t-PA could be a predictor for decreasing prevalence of future strokes after an initial acute ischemic stroke.

Keywords: acute ischemic stroke, t-PA, tissue plasminogen activator, stroke recurrence

 

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