DePaul University Life Trustee George Ruff (BUS ’74) and his wife, Tanya, have made a generous commitment totaling $21 million to support scholarships and DePaul’s Institute of Global Homelessness (IGH). The couple’s George L. and Tanya S. Ruff  Endowed Scholarship follows their George L. Ruff Endowed Scholarship in Hospitality Leadership, deepening their commitment to students. Moreover, in recognition of their contribution to the institute, it will now be known as the George and Tanya Ruff  Institute of Global Homelessness. This article describes how the Ruffs developed their commitment to ending street homelessness.