Faculty Publications – College of Science and Health
Title
Utilizing the PDB and HSAB Theory to Understand Metal Specificity in Trafficking Proteins
Document Type
Article
Publication Date
7-17-2014
Recommended Citation
Rossiter, Clifford; Gunn, Erica; Grice, Kyle A.; Habgood, Laurel Goj; Cass, Marion E.; and Madrahimov, Sherzod. (2014) Utilizing the PDB and HSAB Theory to Understand Metal Specificity in Trafficking Proteins.
https://via.library.depaul.edu/cshfacpubs/81
COinS
Comments
This is an in-class PDB exercise based on the paper "Mechanisms Controlling the Cellular Metal Economy" by Gilston and O'Halloran. Students are asked to visualize the metal binding sites of several proteins discussed in the paper, highlighting unusual metal geometries. After identifying the amino acid residues involved in metal binding, students will discuss the bond structure in terms of HSAB theory.